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Cholesterol Lowering Drug Warning

By Elaine R. Ferguson, M.d.


The most recent data has revealed that more than 45 million Americans and millions more around the world, are taking cholesterol lowering drugs. Most people are informed about the adverse and preventable side effects that cholesterol lowering drugs, also known as statin drugs, are associated. The cause decreased heart muscle function, increased risk of developing diabetes, memory loss, and cognitive decline. These drugs damage muscles, cause weakness and a breakdown of muscle fibers resulting in the release of muscle fiber contents into the bloodstream.

Statin drugs are highly toxic because they stop the cells from producing a key vitamin, CoQ10, which is the cause of the side effects. Relatively low doses of statin drugs dp effectively reduce plasma cholesterol levels. These drugs function by halt an enzyme that changes the chemical HMG-CoA to mevalonate, which is an early and rate-limiting step in cholesterol production. A branch of the cholesterol pathway in animal cells leads to the formation of CoQ10. Also, high levels of statin drugs can reduce CoQ10 in the liver and reduces blood at doses prescribed by physicians.

Regretfully, the vast majority of physicians don't know about the cause of these complications, and could recommend taking CoQ10 supplements to their patients when prescribing these drugs. Pharmaceutical company even has a patent on the drug and CoQ10 combination, since but never released it. In 1989, Merck& Co., makers of lovastatin was awarded patent #4,933,165.

The patent states that Coenzyme Q10 is a part of the respiratory chain and is found in all cells having mitochondria. It is thus an essential ingredient in the production of energy and is very important in muscle function.

Researchers, have measured the levels of Coenzyme Q10 in heart tissue biopsy samples taken from patients with varying stages of damage to the heart muscle. These researchers observed decreasing tissue levels of CoQ10 with increasing severity of the symptoms of cardiac disease. Unfortunately, the FDA doesn't warn consumers of this dangerous and reversible side effect.There are no official warnings in the U.S. regarding CoQ10.

Compared to the U.S., Canadian law requires labeling and clearly warns of CoQ10 depletion and even notes that this nutrient deficiency "could lead to impaired cardiac function in patients with borderline congestive heart failure."




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